ncRNA name | hsa-miR-146a |
ncRNA Category | miRNA |
Disease name | Graves ophthalmopathy |
Species | Homo sapiens |
Tissues/Cell_line | orbital adipose/connective tissue |
Methods | microarray, qRT-PCR, ELISA, Western blot |
Expression pattern | up-regulated |
Functional description | MicroRNA 146a was upregulated by inflammatory stress in orbital fibroblasts. Our results indicated that miR-146a had a positive effect on the anti-inflammatory process. MicroRNA 146a may play a role in the regulation of inflammation in orbital fibroblasts, and may participate in the pathogenesis of GO. |
PubMed ID | 27494344 |
Year | 2016 |
Title | Role of miR-146a in the Regulation of Inflammation in an In Vitro Model of Graves' Orbitopathy. |
Drug-related ncRNA | NO |
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